A new study produced by Wagner Reese looked at state rankings in five categories in order to determine the most healthy and least healthy states.
The data looked at state rankings for air quality, diabetes rates, adult smoking rates, food insecurity rates and obesity rates.
Louisiana was calculated as the second-most unhealthy state, followed by Mississippi.
Louisiana ranked 46th in air quality, 47th in diabetes rates, 43rd in adult smoking rates, 48th in food insecurity rates and 47th in obesity rates, according to the study.
Arkansas, West Virginia and Kentucky are just ahead of Louisiana and Mississippi in the rankings.
The top five healthiest states in the U.S. are Hawaii, taking the top spot, followed by New Hampshire, Washington, Vermont and Massachusetts.
The only southern state to rank in the top half of the rankings, the top 25 healthy states, is Florida.
The study calculated each state’s "index score" by averaging rankings in each of the subcategories (air quality, diabetes rate, smoking rates, food insecurity rates and obesity rates).
Read more about the methodology of the data gathering here.